Search results for "model [interaction]"

showing 10 items of 1495 documents

On a Robin (p,q)-equation with a logistic reaction

2019

We consider a nonlinear nonhomogeneous Robin equation driven by the sum of a \(p\)-Laplacian and of a \(q\)-Laplacian (\((p,q)\)-equation) plus an indefinite potential term and a parametric reaction of logistic type (superdiffusive case). We prove a bifurcation-type result describing the changes in the set of positive solutions as the parameter \(\lambda \gt 0\) varies. Also, we show that for every admissible parameter \(\lambda \gt 0\), the problem admits a smallest positive solution.

local minimizersminimal positive solutionsPure mathematicspositive solutionsGeneral MathematicsType (model theory)Lambda01 natural sciencesPositive solutionSet (abstract data type)Maximum principlesuperdiffusive reactionSettore MAT/05 - Analisi Matematicaindefinite potential0101 mathematicsParametric statisticsMathematicsMinimal positive solutionrobin boundary conditionlcsh:T57-57.97010102 general mathematicsRobin boundary conditionTerm (time)010101 applied mathematicsNonlinear systemmaximum principlelcsh:Applied mathematics. Quantitative methodsLocal minimizerOpuscula Mathematica
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Filozofia jako ćwiczenie duchowe. Coachingowy model uprawiania filozofii

2018

Główną tezą tekstu jest uznanie tzw. modelu coachingowego za pierwotny i wciąż żywy sposób uprawiania filozofii. Twierdzę, że filozofia akademicka, która od kilku stuleci tkwi w tradycji scholastycznej, może być uprawiana w modelu coachingowym. W drugim paragrafie przedstawiam odróżnienie dwóch rodzajów filozofowania: Sokratejskiego – określonego w tekście mianem „coachingowego” – oraz Arystotelesowskiego, nazywanego tutaj „scholastycznym”. W trzecim paragrafie pokazuję, w jaki sposób Wiktor Frankl nawiązuje do coachingowej tradycji uprawiania filozofii w swojej praktyce terapeutycznej. W czwartym przedstawiam przykłady zastosowania modelu coachingowego w dydaktyce filozofii.

logoterapiasumieniecoaching exerciseserceconsciousnessmedytacjamodel coachingowy filozofiilogotherapyscholastic modelspiritual exercisećwiczenia coachingowemodel scholastycznycoaching modelćwiczenie duchoweStudia Philosophiae Christianae
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Mutant HRAS as novel target for MEK and mTOR inhibitors.

2015

HRAS is a frequently mutated oncogene in cancer. However, mutant HRAS as drug target has not been investigated so far. Here, we show that mutant HRAS hyperactivates the RAS and the mTOR pathway in various cancer cell lines including lung, bladder and esophageal cancer. HRAS mutation sensitized toward growth inhibition by the MEK inhibitors AZD6244, MEK162 and PD0325901. Further, we found that MEK inhibitors induce apoptosis in mutant HRAS cell lines but not in cell lines lacking RAS mutations. In addition, knockdown of HRAS by siRNA blocked cell growth in mutant HRAS cell lines. Inhibition of the PI3K pathway alone or in combination with MEK inhibitors did not alter signaling nor had an imp…

mTOR inhibitorMutantBlotting Western610 Medicine & healthApoptosisMice SCIDCell LineProto-Oncogene Proteins p21(ras)chemistry.chemical_compoundCell Line TumorNeoplasmsMedicineAnimalsHumansHRASHRAS mutationsProtein Kinase InhibitorsPI3K/AKT/mTOR pathwayCell ProliferationGeneticsMitogen-Activated Protein Kinase KinasesMEK inhibitorOncogeneCell growthbusiness.industryMEK inhibitorTOR Serine-Threonine KinasesDiphenylamineXenograft Model Antitumor AssaysTumor Burdenlung cancer10219 Clinic for Gastroenterology and HepatologyCell Transformation NeoplasticOncologychemistry10032 Clinic for Oncology and HematologyBenzamidesMutationCancer researchbladder cancer2730 OncologyBenzimidazolesRNA InterferenceSignal transductionGrowth inhibitionbusinessSignal TransductionResearch PaperOncotarget
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Yritysontologioiden mallintaminen ja vertailu

2007

mallintaminenEnterprise OntologyToronto Virtual EnterpriseBusiness Model OntologyontologiayrityksetUML
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Nie każdy nosił w plecaku buławę… hetmańską. Kilka uwag o karierze wojskowej i politycznej Aleksandra Hilarego Połubińskiego w związku z pracą Andrze…

2020

Celem artykułu recenzyjnego jest ocena biografii i Aleksandra Hilarego Połubińskiego pióra Andrzeja A. Majewskiego. Dokonano w nim analizy następujących jej elementów: wykorzystanej bazy źródłowej i literatury, właściwości doboru bohatera, konstrukcji pracy oraz postawionych w niej tez. W przypadku tych ostatnich największe zastrzeżenia wzbudziły: sposób przedstawienia Połubińskiego jako dowódcy wojskowego; sprowadzenie na dalszy plan rozważań jego kariery politycznej; zmarginalizowanie działalności gospodarczej; sposób przedstawienia klienteli Połubińskiego. W połączeniu z przyjętą konstrukcją pracy — chronologiczną, z nadmiernie rozbudowanymi opisami działań wojennych, obniża to ocenę rec…

marshal offi ceLithuanian magnatesmodel of biographyAleksander Hilary PołubińskiGrand Duchy of LithuaniaklientelaWielkie Księstwo Litewskiemagnateria litewskamodel biografi ihetman offi ceurząd hetmańskiurząd marszałkowskiclientageKwartalnik Historyczny
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Personality predicts social dominance in female zebra finches, Taeniopygia guttata, in a feeding context.

2011

6 pages; International audience; Although personality has been defined as a suite of correlated behaviours, most studies of animal personality actually consider correlations between a few traits. We examined the repeatability and correlational structure of five potential personality traits (activity, neophobia, exploratory tendencies, risk-taking behaviour and obstinacy), in female zebra finches. In addition, we assessed to what extent personality influenced social dominance in a feeding context in this gregarious species. All personality traits were found to be highly repeatable within individuals. In addition, except for obstinacy, all of them were related to each other, thus defining a b…

media_common.quotation_subjectContext (language use)hierarchyPersonality psychologydominancefeeding successDevelopmental psychologybehavioural syndrome10127 Institute of Evolutionary Biology and Environmental Studies[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisPersonalityBig Five personality traitsrepeatabilityZebra finchEcology Evolution Behavior and Systematicsmedia_common[ SDE.BE ] Environmental Sciences/Biodiversity and Ecologylife history productivityzebra finchAlternative five model of personalitySocial relationDominance (ethology)1105 Ecology Evolution Behavior and Systematicspersonality570 Life sciences; biology590 Animals (Zoology)Animal Science and Zoologyfalse discovery rate[SDE.BE]Environmental Sciences/Biodiversity and Ecology1103 Animal Science and ZoologyPsychologySocial psychologycompetition[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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Supervisor leadership style, employee regulatory focus, and leadership performance: A perspectivism approach

2019

[EN] Drawing on regulatory focus theory, this research proposes that transformational leadership performance depends on followers' circumstances. The analysis of 125 people from two Spanish service firms reveals that, apart from transformational leadership, the presence of academic education, intrinsic job satisfaction and high customer contact, and the absence of family responsibilities, are core conditions for the presence of high leadership performance. The first contribution of this study is the direct inference of follower's regulatory focus from the observation of individuals' circumstances. The second contribution is that leaders should consider followers' circumstances to adopt a su…

media_common.quotation_subjectFsQCAInferenceKeyWords PlusPerspectivismPerspectivismRegulatory focus theoryTransformational leadershipLeadership styleATTITUDESmedia_commonMarketingWORKGOAL ATTAINMENTSupervisorbusiness.industryRegulatory fitRegulatory focus theoryPublic relationsSERVICESFITCHARISMATIC LEADERSHIPTRANSACTIONAL LEADERSHIPMODELTransformational leadershipService (economics)Tripartite model of securityORGANIZACION DE EMPRESASJob satisfactionbusinessPsychologySET
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Principled animation design improves comprehension of complex dynamics

2016

International audience; Learners can have difficulty in decomposing conventionally designed animations to obtain raw material suitable for building high quality mental models. A composition approach to designing animations based on the Animation Processing Model was developed as a principled alternative to prevailing approaches. Outcomes from studying novel and conventional animation designs (independent variable) were compared with respect to mental model quality, knowledge of local kinematics, and capacity to transfer (dependent variables). Study of a compositional animation that presented material in a contiguous fashion resulted in higher quality mental models of a piano mechanism than …

media_common.quotation_subjectMental modelKinematicscomputer.software_genre050105 experimental psychologyEducationHuman–computer interactionAnimation designDevelopmental and Educational Psychology0501 psychology and cognitive sciencesQuality (business)Computer facial animationMathematicsmedia_commonVariablesMultimedia[SCCO.NEUR]Cognitive science/Neuroscience05 social sciences050301 educationAnimationAnimation processing modelComplexityComprehensionComplex dynamicsComposition approachMental model acquisition[ SCCO.NEUR ] Cognitive science/Neuroscience0503 educationcomputer
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Physical activity and sense of coherence : a meta-analysis

2020

The salutogenic model of health proposes that sense of coherence, a multi-dimensional construct representing individuals’ perceptions that their environment is comprehensible, manageable, and meaningful, is a key determinant of stress management and well-being. Generalized resistance resources such as preventive health orientation, material resources, and social support are proposed as determinants of sense of coherence. Health behaviors, particularly physical activity, are proposed as indicators of a preventive health orientation and predictors of sense of coherence. We synthesized research on the relationship between physical activity and sense of coherence using three-level meta-analysis…

media_common.quotation_subjectPhysical activityphysical activitysense of coherenceliikuntakoherenssi050105 experimental psychology03 medical and health sciences0302 clinical medicinehealth behaviorPerception0501 psychology and cognitive sciencesApplied Psychologymedia_commonexercise05 social sciences030229 sport sciencessalutogenic model of healthMeta-analysisterveyskäyttäytyminengeneralized resistance resourcesHealth behaviorPsychologyConstruct (philosophy)fyysinen aktiivisuusCognitive psychologySense of coherence
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The relationship between Gray's and Eysenck's personality spaces

1993

In a sample of 171 healthy volunteers, the present study examined the relationships between questionnaire measures of trait anxiety, punishment sensitivity, and impulsivity with the measures from the Eysenck Personality Questionnaire (EPQ). This was undertaken in order to explore the relative location of the personality dimensions central to the ideas of Gray and Eysenck. Results confirmed that the behavioural inhibition personality dimension (anxiety) lies at a non-negligible angle relative to neuroticism (N) especially when measured via special purpose questionnaires. This dimension also appeared largely independent of psychoticism (P) which suggests limits on the importance of a hypoacti…

media_common.quotation_subjectPsychopathyAlternative five model of personalityImpulsivitymedicine.diseaseNeuroticismEysenck Personality QuestionnaireDevelopmental psychologyPsychoticismmedicinePersonalitymedicine.symptomPersonality testPsychologyGeneral Psychologymedia_commonPersonality and Individual Differences
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